Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RHEB | Q15382 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPRG | P23470 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710082 | 0.85 | SIRT1 (0.50) | MEN1MAPTKMT2ARHEBKDM4E | |
| SCHEMBL232529 | 0.82 | MEN1 (0.53) | MEN1GAAMAPTHPGDKMT2A | |
| SCHEMBL6556776 | 0.80 | LMNA (0.56) | MEN1GAAMAPTHPGDKMT2A | |
| SCHEMBL11760014 | 0.77 | IDO1 (0.51) | MEN1GAAMAPTHPGDKMT2A | |
| SCHEMBL11758399 | 0.77 | SLC6A9 (0.47) | MEN1GAAMAPTHPGDKMT2A | |
| SCHEMBL11013368 | 0.76 | SIRT1 (0.51) | MEN1MAPTKMT2AKDM4E | |
| SCHEMBL20286150 | 0.76 | PTPRC (0.45) | MEN1MAPTKMT2ARHEBKDM4E | |
| SCHEMBL30402308 | 0.75 | MEN1 (0.53) | MEN1GAAMAPTHPGDKMT2A | |
| SCHEMBL29269707 | 0.75 | MEN1 (0.53) | MEN1GAAMAPTHPGDKMT2A | |
| SCHEMBL30402483 | 0.73 | MEN1 (0.51) | MEN1GAAMAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1197491-B1 | Thioxanthenone antitumor agents | SANOFI AVENTIS (FR) | 2004-12-29 | — | — | EP | disclosed |
| EP-0917458-B1 | LYOPHILIZED THIOXANTHENONE ANTIMUMOR AGENTS | SANOFI SYNTHELABO INC (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0882723-B1 | Thioxanthenone antitumor agents | SANOFI SYNTHELABO (FR) | 2002-07-31 | — | — | EP | disclosed |
| EP-1197491-A1 | Thioxanthenone antitumor agents | SANOFI-SYNTHELABO (FR) | 2002-04-17 | — | — | EP | disclosed |
| EP-0619315-B1 | Thioxanthenone antitumor agents | SANOFI SA (FR) | 1999-06-09 | — | — | EP | disclosed |
| EP-0917458-A1 | LYOPHILIZED THIOXANTHENONE ANTIMUMOR AGENTS | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| EP-0882723-A1 | Thioxanthenone antitumor agents | SANOFI (FR) | 1998-12-09 | — | — | EP | disclosed |
| US-5665760-A | Lyophilized thioxanthenone antitumor agents | SANOFI WINTHROP, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| WO-1997010809-A1 | LYOPHILIZED THIOXANTHENONE ANTIMUMOR AGENTS | SANOFI (FR) | 1997-03-27 | — | — | WO | disclosed |
| US-5380749-A | Thioxanthenone antitumor agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0619315-A1 | Thioxanthenone antitumor agents | STERLING WINTHROP INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5346917-A | For mammals | STERLING WINTHROP INC. (US) | 1994-09-13 | — | — | US | disclosed |