Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557108 | 0.89 | TACR1 (0.77) | TACR1CYP2D6 | |
| SCHEMBL22272194 | 0.86 | TACR1 (0.77) | TACR1CYP2D6 | |
| SCHEMBL9295001 | 0.86 | TACR1 (0.77) | TACR1CYP2D6 | |
| SCHEMBL31401661 | 0.86 | TACR1 (0.77) | TACR1CYP2D6 | |
| SCHEMBL6554936 | 0.86 | TACR1 (1.00) | TACR1CYP2D6 | |
| SCHEMBL6554939 | 0.86 | TACR1 (1.00) | TACR1CYP2D6 | |
| SCHEMBL6554931 | 0.86 | TACR1 (1.00) | TACR1CYP2D6 | |
| SCHEMBL6556858 | 0.85 | TACR1 (0.76) | TACR1CYP2D6 | |
| SCHEMBL6555029 | 0.85 | TACR1 (0.76) | TACR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7480501 | 0.85 | TACR1 (0.74) | TACR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721778-B1 | NK-1 receptor antagonists for the treatment of neuronal injury and stroke | PFIZER (US) | 2004-03-03 | — | — | EP | claimed |
| US-6194436-B1 | THERAPY FOR LUNG CANCER | PFIZER INC. | 2001-02-27 | — | — | US | claimed |
| EP-0854720-B1 | NK-1 RECEPTOR ANTAGONISTS FOR PREVENTION OF NEUROGENIC INFLAMMATION IN GENE THERAPY | PFIZER (US) | 1999-08-04 | — | — | EP | claimed |
| EP-0773026-A2 | NK-1 receptor antagonists for the treatment of cancer | PFIZER INC. (US) | 1997-05-14 | — | — | EP | claimed |
| EP-0659409-A2 | Substance 1 antagonists for the inhibition of angiogenesis | PFIZER INC. (US) | 1995-06-28 | — | — | EP | claimed |