Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 6/20 | 0.36 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | BHMT | Q93088 | 6/20 | 0.35 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6557109 | 1.00 | RNPEP (0.40) | RNPEPNOS2NOS1NOS3BHMT | |
| Methionine SCHEMBL8589231 | 0.87 | BHMT (0.47) | RNPEPNOS2NOS1NOS3BHMT | |
| Racemethionine SCHEMBL8589228 | 0.87 | BHMT (0.47) | RNPEPNOS2NOS1NOS3BHMT | |
| Methionine SCHEMBL8763034 | 0.87 | BHMT (0.47) | RNPEPNOS2NOS1NOS3BHMT | |
| SCHEMBL1416384 | 0.87 | — | — | |
| SCHEMBL3316021 | 0.87 | — | — | |
| SCHEMBL358438 | 0.87 | — | — | |
| SCHEMBL9223289 | 0.87 | RNPEP (0.45) | RNPEPNOS2NOS1NOS3BHMT | |
| Acetic Acid SCHEMBL10586335 | 0.85 | RNPEP (0.45) | RNPEPNOS2NOS1NOS3BHMT | |
| Acetic Acid SCHEMBL10586329 | 0.85 | RNPEP (0.45) | RNPEPNOS2NOS1NOS3BHMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797447-B1 | HUMAN CANCER INHIBITORY PENTAPEPTIDE HETEROCYCLIC AND HALOPHENYL AMIDES | UNIV ARIZONA (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-0797447-A4 | HUMAN CANCER INHIBITORY PENTAPEPTIDE HETEROCYCLIC AND HALOPHENYL AMIDES | UNIV ARIZONA (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0797447-A1 | HUMAN CANCER INHIBITORY PENTAPEPTIDE HETEROCYCLIC AND HALOPHENYL AMIDES | ARIZONA BOARD OF REGENTS (US) | 1997-10-01 | — | — | EP | disclosed |
| US-5663149-A | ANTICARCINOGENIC AGENTS RELATED TO DOLASTATIN | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1996018408-A1 | HUMAN CANCER INHIBITORY PENTAPEPTIDE HETEROCYCLIC AND HALOPHENYL AMIDES | ARIZONA BOARD OF REGENTS (US) | 1996-06-20 | — | — | WO | disclosed |