Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | BCAT1 | P54687 | 7/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571692 | 0.88 | BCAT1 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6557384 | 0.85 | BCAT1 (0.45) | BCAT1BCAT2MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL9571699 | 0.78 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9587737 | 0.78 | BCAT1 (0.42) | BCAT1BCAT2MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL9653564 | 0.77 | BCAT1 (0.50) | BCAT1BCAT2 | |
| SCHEMBL7844546 | 0.77 | BCAT1 (0.41) | BCAT1BCAT2MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL7973578 | 0.76 | BCAT1 (0.43) | BCAT1BCAT2MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL9652957 | 0.76 | BCAT1 (0.48) | BCAT1BCAT2 | |
| SCHEMBL9423296 | 0.76 | BCAT1 (0.46) | BCAT1BCAT2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9581280 | 0.74 | BCAT1 (0.50) | BCAT1BCAT2MAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021417-B1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| US-6362337-B1 | ACYLATING A HYDROXYPHENYLURACIL COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| US-6277789-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
| EP-1021417-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999012913-A1 | SUBSTITUTED PHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |
| EP-0545206-A1 | N-Aryl-nitrogenheterocycles and their use as herbicides | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |