Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 6/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463992 | 1.00 | GPR84 (0.44) | GPR84CES1PARP1BCL2L1BAD | |
| SCHEMBL18965866 | 0.98 | GPR84 (0.42) | GPR84CES1PARP1BCL2L1BAD | |
| SCHEMBL18965964 | 0.98 | GPR84 (0.42) | GPR84CES1PARP1BCL2L1BAD | |
| SCHEMBL6557228 | 0.83 | CES1 (0.39) | CES1PARP1BCL2L1BADNQO1 | |
| SCHEMBL6557255 | 0.81 | PARP1 (0.39) | CES1PARP1BCL2L1BADNQO1 | |
| SCHEMBL6557449 | 0.81 | CES1 (0.38) | CES1PARP1BCL2L1BADNQO1 | |
| SCHEMBL6557223 | 0.81 | CES1 (0.38) | CES1PARP1BCL2L1BADNQO1 | |
| SCHEMBL887350 | 0.81 | PARP1 (0.34) | CES1PARP1GRIA1GRIA2GRIA3 | |
| SCHEMBL887383 | 0.81 | CES1 (0.33) | CES1PARP1 | |
| SCHEMBL887276 | 0.78 | GPR84 (0.31) | GPR84CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020007342-A1 | APPLICATION OF BIPHENYL PHOSPHATE COMPOUND AS GPR84 ANTAGONIST | 中国科学院上海药物研究所 | 2020-01-09 | — | — | WO | disclosed |
| US-7517828-B2 | Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-7517828-B2 | Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst | TOAGOSEI CO., LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| EP-1038877-B1 | Binaphthol monophosphoric acid derivative and its use | TOSOH CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6274745-B1 | CATALYST | TOSOH CORPORATION (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-1038877-A1 | Binaphthol monophosphoric acid derivative and its use | Tosoh Corporation (JP) | 2000-09-27 | — | — | EP | disclosed |