Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556030 | 0.97 | L3MBTL1 (0.52) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6557264 | 0.96 | KDM4E (0.56) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6555798 | 0.93 | KDM4E (0.59) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6555771 | 0.92 | KDM4E (0.54) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6555784 | 0.92 | KDM4E (0.58) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6556005 | 0.91 | L3MBTL1 (0.57) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6556105 | 0.90 | KDM4E (0.55) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6555895 | 0.89 | KDM4E (0.59) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6557982 | 0.88 | L3MBTL1 (0.58) | L3MBTL1KDM4EALOX15TSHRTDP1 | |
| SCHEMBL6555770 | 0.87 | KDM4E (0.59) | L3MBTL1KDM4EALOX15TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073643-B1 | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-12-29 | — | — | EP | claimed |