Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | TK2 | O00142 | 8/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5148562 | 0.77 | KIF11 (0.51) | KIF11HRH4TK2SLC6A1TK1 | |
| SCHEMBL5150423 | 0.76 | KIF11 (0.43) | KIF11HRH4SLC6A1 | |
| SCHEMBL5151844 | 0.76 | KIF11 (0.54) | KIF11HRH4TK2SLC6A1TK1 | |
| SCHEMBL5147531 | 0.75 | KIF11 (0.42) | KIF11HRH4TK2SLC6A1TK1 | |
| SCHEMBL5148643 | 0.74 | KIF11 (0.51) | KIF11HRH4TK2SLC6A1TK1 | |
| SCHEMBL5147565 | 0.73 | KIF11 (0.40) | KIF11HRH4TK2SLC6A1TK1 | |
| SCHEMBL5150384 | 0.71 | KIF11 (0.38) | KIF11HRH4SLC6A1 | |
| SCHEMBL5150392 | 0.71 | KIF11 (0.38) | KIF11HRH4SLC6A1 | |
| SCHEMBL5151740 | 0.70 | NQO2 (0.39) | KIF11TSHR | |
| SCHEMBL5150660 | 0.69 | KIF11 (0.36) | KIF11HRH4TK2SLC6A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392704-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090364-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |