Ethylene Glycol

Ethylene Glycol

SCHEMBL6557487

O=C(Cl)CCCCCCCCC(=O)Cl.OCCO

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.62
ALDH1A1 P00352 4/20 0.62
TP53 P04637 1/20 0.52
GPR84 Q9NQS5 4/20 0.46
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 2/20 0.46
LMNA P02545 2/20 0.40
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CAMK2A Q9UQM7 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL6557377 0.97 TSHR (0.57) TSHRALDH1A1TP53GPR84FFAR1
SCHEMBL21295305 0.91 TSHR (0.59) TSHRALDH1A1TP53GPR84FFAR1
1,6-Hexanediol SCHEMBL6558431 0.91 TSHR (0.59) TSHRALDH1A1TP53GPR84FFAR1
SCHEMBL10455968 0.91 TSHR (0.59) TSHRALDH1A1TP53GPR84FFAR1
SCHEMBL202630 0.91
SCHEMBL496221 0.90 TSHR (0.72) TSHRALDH1A1TP53GPR84FFAR1
SCHEMBL495310 0.90 TSHR (0.72) TSHRALDH1A1TP53GPR84FFAR1
SCHEMBL2154814 0.90 TSHR (0.72) TSHRALDH1A1TP53GPR84FFAR1
SCHEMBL494288 0.90 TSHR (0.72) TSHRALDH1A1TP53GPR84FFAR1
SCHEMBL466419 0.90 TSHR (0.72) TSHRALDH1A1TP53GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0916394-B1 Method of manufacturing modified particles and manufacturing device therefor SHARP KK (JP) 2004-03-10 EP disclosed
US-6194487-B1 EXPOSURE OF PARTICLES TO SUPERSATURATED VAPOR OF MONOMERS, CONDENSATION AND POLYMERIZATION ON THE SURFACE SHARP KABUSHIKI KAISHA (JP) 2001-02-27 US disclosed
EP-0916394-A2 Method of manufacturing modified particles and manufacturing device therefor Sharp Kabushiki Kaisha (JP) 1999-05-19 EP disclosed