SCHEMBL494288

SCHEMBL494288

O=C(Cl)CCCCCCCCCCCCC(=O)Cl

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.72
ALDH1A1 P00352 4/20 0.72
TP53 P04637 1/20 0.61
LMNA P02545 2/20 0.47
NFKB1 P19838 1/20 0.47
PMP22 Q01453 1/20 0.47
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
GPR84 Q9NQS5 5/20 0.38
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
FFAR1 O14842 2/20 0.38
FFAR4 Q5NUL3 2/20 0.38
PPARG P37231 6/20 0.36
PPARD Q03181 6/20 0.36
PPARA Q07869 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL495403 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL7329781 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL494763 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL6057206 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL466419 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL495310 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL496221 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL2154041 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL2154814 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL2154590 1.00 TSHR (0.72) TSHRALDH1A1TP53LMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240092780-A1 ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD ANKH LIFE SCIENCES LIMITED (IE) 2024-03-21 US claimed
WO-2024050395-A1 ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD ANKH LIFE SCIENCES LIMITED (IE) 2024-03-07 WO claimed
CN-117534834-A Polymer, preparation method and application thereof, and intrinsic low-temperature curing negative photoresist 上海交通大学 2024-02-09 CN claimed
CN-117423954-A Lithium battery diaphragm and preparation method thereof 安徽利科新材料科技有限公司 2024-01-19 CN claimed
JP-59104339-A None JP disclosed
JP-59199650-A None JP disclosed
EP-4688940-A1 HIGH-VOLTAGE RESISTANT POLYAMIDE COMPOSITION BASF SE (DE) 2026-02-11 EP disclosed
WO-2024208771-A1 HIGH-VOLTAGE RESISTANT POLYAMIDE COMPOSITION BASF SE (DE) 2024-10-10 WO disclosed
US-20240092780-A1 ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD ANKH LIFE SCIENCES LIMITED (IE) 2024-03-21 US disclosed
CN-117534834-A Polymer, preparation method and application thereof, and intrinsic low-temperature curing negative photoresist 上海交通大学 2024-02-09 CN disclosed
CN-117209753-A Nanoscale polyamide particles and preparation method thereof 安徽利科新材料科技有限公司 2023-12-12 CN disclosed
WO-2022144920-A1 ATOVAQUONE PRODRUGS IPCA LABORATORIES LIMITED (IN) 2022-07-07 WO disclosed
US-5705635-A BOLAFORM GLYCOLIPID JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1998-01-06 US disclosed
US-5670493-A ANGIOGENESIS INHIBITORS ADIR ET COMPAGNIE (FR) 1997-09-23 US disclosed
US-5424349-A Tertiary amides with low volatility and good thermal stability ALBEMARLE CORPORATION (US) 1995-06-13 US disclosed
WO-1992016495-A1 AMIDE ANTIOXIDANTS ETHYL CORPORATION (US) 1992-10-01 WO disclosed
JP-S59199650-A PRODUCTION OF LONG-CHAIN DIKETONE NIPPON MINING CO LTD 1984-11-12 JP disclosed
JP-S59104339-A PREPARATION OF 2,15-HEXADECANEDIONE NIPPON MINING CO LTD 1984-06-16 JP disclosed
US-4087481-A INJECTION MOLDING MATERIALS THE UPJOHN COMPANY (US) 1978-05-02 US disclosed
US-4072665-A Polyamide from arylene diamine, isophthalic acid and alkylene dicarboxylic acid THE UPJOHN COMPANY (US) 1978-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092780-A1 ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD DRD2, HNMT, DRD1 TSHR 2581/4885ALDH1A1 1683/4885TP53 2964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.