Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 7/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556361 | 0.91 | MAPT (0.42) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7152432 | 0.91 | MAPT (0.41) | CTRCKDM4EALDH1A1CMA1MEN1 | |
| SCHEMBL6558388 | 0.90 | KDM4E (0.49) | CTRCKDM4EALDH1A1GAAPKM | |
| SCHEMBL6556282 | 0.88 | KDM4E (0.38) | KDM4EALDH1A1GAAPKMMEN1 | |
| SCHEMBL6558315 | 0.86 | MEN1 (0.42) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6556504 | 0.84 | CSNK1D (0.37) | KDM4EALDH1A1GAAPKMMEN1 | |
| SCHEMBL6556234 | 0.83 | ELANE (0.39) | KDM4EALDH1A1GAA | |
| SCHEMBL6557511 | 0.83 | P2RX3 (0.41) | KDM4EALDH1A1KMT2AHPGDMAPT | |
| SCHEMBL6558138 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1GAAGRIN1GRIN2B | |
| SCHEMBL6558284 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826671-B1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0826671-A1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | THE GREEN CROSS CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |