Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 7/20 | 0.46 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | INPP5B | P32019 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17173609 | 0.72 | CES1 (0.41) | CES1STSPARP1BCL2L1BAD | |
| SCHEMBL17770807 | 0.72 | KDM4E (0.46) | CES1KDM4EALDH1A1HPGD | |
| SCHEMBL3917751 | 0.70 | INPPL1 (0.36) | INPPL1INPP5AAKT1SRCINPP5B | |
| SCHEMBL13185845 | 0.69 | KMT2A (0.39) | CES1KDM4EALDH1A1PARP1 | |
| SCHEMBL3626119 | 0.69 | CES1 (0.36) | CES1KDM4EPARP1BCL2L1BAD | |
| SCHEMBL16237015 | 0.69 | KMT2A (0.47) | USP2ALDH1A1HSD17B10 | |
| SCHEMBL6379376 | 0.68 | INPPL1 (0.55) | INPPL1INPP5AAKT1SRCINPP5B | |
| SCHEMBL15766043 | 0.68 | CES1 (0.38) | CES1PARP1BCL2L1BAD | |
| SCHEMBL16239266 | 0.68 | KMT2A (0.46) | USP2ALDH1A1HSD17B10 | |
| SCHEMBL16812541 | 0.68 | ALDH1A1 (0.36) | CES1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038877-B1 | Binaphthol monophosphoric acid derivative and its use | TOSOH CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6274745-B1 | CATALYST | TOSOH CORPORATION (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-1038877-A1 | Binaphthol monophosphoric acid derivative and its use | Tosoh Corporation (JP) | 2000-09-27 | — | — | EP | disclosed |