Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873730 | 0.83 | MCHR1 (0.55) | MCHR1KCNH2MAPT | |
| SCHEMBL5873725 | 0.83 | MCHR1 (0.55) | MCHR1KCNH2MAPT | |
| SCHEMBL5873497 | 0.81 | MCHR1 (0.52) | MCHR1KCNH2MAPT | |
| SCHEMBL5873503 | 0.81 | MCHR1 (0.52) | MCHR1KCNH2MAPT | |
| Hydrochloric Acid SCHEMBL5873477 | 0.78 | MAPT (0.62) | MCHR1MAPT | |
| Hydrochloric Acid SCHEMBL5873480 | 0.78 | MAPT (0.62) | MCHR1MAPT | |
| SCHEMBL5873489 | 0.77 | MCHR1 (0.52) | MCHR1KCNH2MAPT | |
| SCHEMBL5873494 | 0.77 | MCHR1 (0.52) | MCHR1KCNH2MAPT | |
| SCHEMBL22499908 | 0.76 | PDE10A (0.46) | MCHR1 | |
| SCHEMBL22499905 | 0.76 | PDE10A (0.46) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450801-A2 | 2-AMINOQUINOLINE COMPOUNDS | Merck & Co., Inc. (US) | 2004-09-01 | — | — | EP | claimed |
| WO-2003045313-A2 | 2-AMINOQUINOLINE COMPOUNDS | MERCK & CO. INC. (US) | 2003-06-05 | — | — | WO | claimed |