Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704361 | 0.93 | GAA (0.61) | GAAKDM4EALDH1A1LMNANPC1 | |
| Hydrochloric Acid SCHEMBL1391938 | 0.92 | GAA (0.59) | GAAKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL12939717 | 0.91 | GAA (0.69) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16680003 | 0.87 | LMNA (0.57) | GAAKDM4EALDH1A1LMNAAPOBEC3A | |
| SCHEMBL12207333 | 0.87 | LMNA (0.57) | GAAKDM4EALDH1A1LMNAAPOBEC3A | |
| SCHEMBL31681325 | 0.84 | GAA (0.68) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1714190 | 0.83 | GAA (0.54) | GAAKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL12939715 | 0.83 | MCOLN3 (0.69) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4963034 | 0.82 | GAA (0.53) | GAAKDM4EALDH1A1LMNANPC1 | |
| Hydrochloric Acid SCHEMBL4963047 | 0.82 | GAA (0.53) | GAAKDM4EALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436255-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003024924-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-03-27 | — | — | WO | claimed |