Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031270 | 0.95 | TSHR (0.58) | MAOBKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL17445905 | 0.92 | ATM (0.60) | MAOBKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL18235025 | 0.92 | DRD4 (0.57) | MAOBKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL8417765 | 0.90 | KCNA3 (0.61) | MAOBKDM4EALDH1A1PTGS2LTA4H | |
| SCHEMBL7898603 | 0.89 | ATM (0.58) | MAOBKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL17465617 | 0.89 | ATM (0.58) | MAOBKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL6268340 | 0.88 | KDM4E (0.52) | MAOBKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL410729 | 0.88 | KDM4E (0.52) | MAOBKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL1697534 | 0.87 | KDM4E (0.50) | MAOBKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL21876667 | 0.86 | NPC1 (0.59) | MAOBKDM4EALDH1A1DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958288-B1 | PHOTOCHROMIC NAPHTOPYRANE COLORANTS, METHOD FOR THE PRODUCTION AND USE THEREOF, PHOTOCHROMIC OBJECT | RODENSTOCK GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6146554-A | FOR PHOTOCHROMIC PLASTIC LENSES IN MASS-DYEING PROCESSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2000-11-14 | — | — | US | disclosed |
| US-4223169-A | Process for polybrominating bisphenoxyalkanes | FERRO CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |