Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208077 | 0.98 | PPARA (0.56) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL11312936 | 0.94 | PPARA (0.64) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL10419238 | 0.89 | PPARA (0.51) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL6557873 | 0.85 | RARB (0.51) | HDAC1HDAC2 | |
| SCHEMBL10420227 | 0.85 | PPARA (0.48) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL10419280 | 0.85 | PPARA (0.49) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL27775192 | 0.84 | PPARA (0.54) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL10420724 | 0.84 | PPARA (0.54) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL27433873 | 0.84 | PPARA (0.54) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL7828484 | 0.84 | PPARG (0.50) | PPARAPPARGHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |