Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11177014 | 0.98 | EPHX1 (0.50) | EPHX1SMN1; SMN2GPR84FFAR1FNTA | |
| SCHEMBL7597231 | 0.98 | EPHX1 (0.50) | EPHX1SMN1; SMN2GPR84FFAR1FNTA | |
| SCHEMBL9338351 | 0.90 | SMN1; SMN2 (0.42) | EPHX1SMN1; SMN2GPR84FFAR1FNTA | |
| SCHEMBL28576365 | 0.88 | EPHX1 (0.45) | EPHX1SMN1; SMN2GPR84FFAR1FNTA | |
| SCHEMBL3433811 | 0.86 | SMN1; SMN2 (0.40) | EPHX1SMN1; SMN2GPR84FFAR1FNTA | |
| SCHEMBL1070438 | 0.86 | EPHX1 (0.44) | EPHX1SMN1; SMN2GPR84FFAR1FNTA | |
| SCHEMBL3433807 | 0.86 | SMN1; SMN2 (0.40) | EPHX1SMN1; SMN2GPR84FFAR1FNTA | |
| SCHEMBL9027136 | 0.85 | EPHX1 (0.42) | EPHX1SMN1; SMN2GPR84FFAR1FNTA | |
| SCHEMBL7348111 | 0.83 | HDAC1 (0.40) | EPHX1SMN1; SMN2GPR84FFAR1MAPT | |
| SCHEMBL9025525 | 0.83 | EPHX1 (0.41) | EPHX1SMN1; SMN2GPR84FFAR1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073795-A | Synthesis of tryptophans | HOFFMANN-LA ROCHE INC. (US) | 1978-02-14 | — | — | US | claimed |
| EP-1069109-B1 | Process for production of optically active N-protected-N-methyl-phenylalanine derivative | AJINOMOTO KK (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6342629-B1 | ENANTIOMORPHS FROM REACTION OF CYCLOHEXYLAMINE OR DICYCLOHEXYLAMINE AND ISOLATION | AJINOMOTO CO., INC. (JP) | 2002-01-29 | — | — | US | disclosed |
| EP-1069109-A1 | Process for production of optically active N-protected-N-methyl-phenylalanine derivative | Ajinomoto Co., Inc. (JP) | 2001-01-17 | — | — | EP | disclosed |
| WO-2000053569-A1 | METHOD FOR PREPARING 2-2[(4-ALKYLPHENYL)-ETHYL]-2-AMINO-PROPANEDIOL AND INTERMEDIATES USEFUL IN SUCH PREPARATION | HANGZHOU ZHONGMEI HUADONG PHARMACEUTICAL CO. LTD. (CN) | 2000-09-14 | — | — | WO | disclosed |
| US-4316847-A | ARTIFICIAL SWEETENING | HOFFMANN-LA ROCHE INC. (US) | 1982-02-23 | — | — | US | disclosed |
| US-4256641-A | ALKYL ALPHA-CARBOXAMIDOINDOLE-3-ACRYLATES MADE FROM 3-INDOLECARBOXALDEHYDES AND MONOALKYL CARBOXAMIDOMALONATES | HOFFMANN-LA ROCHE INC. (US) | 1981-03-17 | — | — | US | disclosed |
| US-4140697-A | ARTIFICIAL SWEETENER | HOFFMANN-LA ROCHE INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4073795-A | Synthesis of tryptophans | HOFFMANN-LA ROCHE INC. (US) | 1978-02-14 | — | — | US | disclosed |