Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433811 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2EPHX1FNTAFNTBNAAA | |
| SCHEMBL6557889 | 0.86 | EPHX1 (0.46) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL1070438 | 0.85 | EPHX1 (0.44) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL7597231 | 0.84 | EPHX1 (0.50) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL11177014 | 0.84 | EPHX1 (0.50) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL9027136 | 0.84 | EPHX1 (0.42) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL9025525 | 0.82 | EPHX1 (0.41) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL9338351 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL28576365 | 0.79 | EPHX1 (0.45) | SMN1; SMN2EPHX1FNTAFNTBGPR84 | |
| SCHEMBL18064432 | 0.76 | CES2 (0.38) | PLA2G2APLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117320-B1 | CHEMICALS PROMOTING THE GROWTH OF N-ACYLHOMOSERINE LACTONE-DEGRADING BACTERIA | CENTRE NAT RECH SCIENT (FR) | 2017-03-22 | — | — | EP | disclosed |
| US-20170043020-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-02-16 | — | — | US | disclosed |
| EP-2842565-B1 | Antibody-mediated disruption of quorum sensing in bacteria | SCRIPPS RESEARCH INST (US) | 2016-08-24 | — | — | EP | disclosed |
| US-9394371-B2 | Antibody-mediated disruption of quorum sensing in bacteria | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-19 | — | — | US | disclosed |
| EP-2842565-A1 | Antibody-mediated disruption of quorum sensing in bacteria | The Scripps Research Institute (US) | 2015-03-04 | — | — | EP | disclosed |
| CN-104211775-A | Antibody-mediated disruption of quorum sensing in bacteria | SCRIPPS RESEARCH INST | 2014-12-17 | — | — | CN | disclosed |
| EP-2211889-B1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | SCRIPPS RESEARCH INST (US) | 2014-08-20 | — | — | EP | disclosed |
| CN-101835484-B | Antibody-mediated disruption of bacterial quorum sensing | SCRIPPS RESEARCH INST | 2014-07-16 | — | — | CN | disclosed |
| US-8354265-B2 | Chemicals promoting the growth of N-acylhomoserine lactone-degrading bacteria | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-15 | — | — | US | disclosed |
| US-20100291093-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-11-18 | — | — | US | disclosed |
| CN-101835484-A | Antibody-mediated disruption of bacterial quorum sensing | SCRIPPS RESEARCH INST | 2010-09-15 | — | — | CN | disclosed |
| EP-2211889-A2 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | The Scripps Research Institute (US) | 2010-08-04 | — | — | EP | disclosed |
| US-20100050719-A1 | CHEMICALS PROMOTING THE GROWTH OF N-ACYLHOMOSERINE LACTONE-DEGRADING BACTERIA | COMITE ECONOMIQUE AGRICOLE PRODUCTION DES PLANTS DU NORD (COMITE NORD POMME DE TERRE) (FR) | 2010-03-04 | — | — | US | disclosed |
| WO-2009055054-A2 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | JANDA KIM D (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100050719-A1 | CHEMICALS PROMOTING THE GROWTH OF N-ACYLHOMOSERINE LACTONE-DEGRADING BACTERIA | PGLS, BPHL, AHCYL1 | SMN1; SMN2 4868/4885EPHX1 463/4885FNTA 371/4885 |
| US-20170043020-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | CD47, TLR5, ANTXR2 | SMN1; SMN2 4863/4885EPHX1 3491/4885FNTA 136/4885 |
| US-20100291093-A1 | ANTIBODY-MEDIATED DISRUPTION OF QUORUM SENSING IN BACTERIA | CD47, BCR, TLR5 | SMN1; SMN2 4853/4885EPHX1 3887/4885FNTA 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.