SCHEMBL6558445

SCHEMBL6558445

CCCCc1ccc(Oc2ccc(N)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
CYP3A4 P08684 1/20 0.54
TSHR P16473 1/20 0.54
TEAD4 Q15561 1/20 0.50
HTR2A P28223 1/20 0.50
MAPT P10636 3/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MAOB P27338 2/20 0.48
POLB P06746 1/20 0.48
GFER P55789 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
S1PR1 P21453 1/20 0.47
S1PR3 Q99500 1/20 0.47
MAOA P21397 1/20 0.47
CA2 P00918 1/20 0.46
CYP19A1 P11511 1/20 0.46
SKP2 Q13309 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8468719 0.94 HTR2A (0.58) ALDH1A1TDP1CYP3A4TSHRTEAD4
SCHEMBL8466652 0.93 HTR2A (0.61) ALDH1A1TDP1CYP3A4TSHRHTR2A
SCHEMBL8504735 0.93 HTR2A (0.61) ALDH1A1TDP1CYP3A4TSHRHTR2A
SCHEMBL8467844 0.93 HTR2A (0.61) ALDH1A1TDP1CYP3A4TSHRHTR2A
SCHEMBL8467532 0.93 HTR2A (0.61) ALDH1A1TDP1CYP3A4TSHRHTR2A
SCHEMBL8356640 0.93 HTR2A (0.61) ALDH1A1TDP1CYP3A4TSHRHTR2A
SCHEMBL8500850 0.93 HTR2A (0.61) ALDH1A1TDP1CYP3A4TSHRHTR2A
SCHEMBL8468968 0.93 HTR2A (0.61) ALDH1A1TDP1CYP3A4TSHRHTR2A
SCHEMBL8501688 0.93 HTR2A (0.61) ALDH1A1TDP1CYP3A4TSHRHTR2A
SCHEMBL145761 0.90 LTA4H (0.52) ALDH1A1CYP3A4HTR2ASMN1; SMN2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109823016-B Polyimide composite film and preparation method thereof 宁波激智科技股份有限公司 2020-12-01 CN claimed
CN-109823016-B Polyimide composite film and preparation method thereof 宁波激智科技股份有限公司 2020-12-01 CN disclosed
EP-0816914-B1 Diazonium salt for thermosensitive recording medium OKI ELECTRIC IND CO LTD (JP) 2004-03-17 EP disclosed
US-5935756-A Diazonium salt for thermosensitive recording medium OKI ELECTRIC INDUSTRY CO., LTD. (JP) 1999-08-10 US disclosed
US-5928733-A Active-matrix liquid crystal display HITACHI, LTD. (JP) 1999-07-27 US disclosed
US-5907005-A SUITABLE FOR PRODUCING A LIQUID CRYSTAL ALIGNING FILM WITH SPECIFIC THICKNESS CONSISTS OF POLYAMIC ACID OR POLYIMIDE, AND A SOLVENT CONSISTS OF N-METHYL-PYRROLIDONE AND DIMETHYL IMIDAZOLIDINONE, AN ALKYL LACTATE AND AN ETHER CHISSO CORPORATION (JP) 1999-05-25 US disclosed
US-5821319-A COMPRISING STRUCTURAL UNITS DERIVED FROM PYROMELLITIC ANHYDRIDE, TEREPHTHALOYL CHLORIDE, 1,3-BIS/4-(4-AMINOPHENOXY)-ALPHA,ALPHA-DIMETHYLBENZYL/BENZENE MITSUI CHEMICALS, INC. (JP) 1998-10-13 US disclosed
US-5798810-A RUBBING, IRRADIATING AND SEALING CHISSO CORPORATION (JP) 1998-08-25 US disclosed
US-5744203-A POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
EP-0816914-A2 Diazonium salt for thermosensitive recording medium Oki Electric Industry Co., Ltd. (JP) 1998-01-07 EP disclosed
US-5670084-A Alignment layer material for liquid crystal display devices HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US disclosed
US-5514748-A POLYMER FOR SLIDING CONTAINING PHENOLIC RESINS AND LUBRICANTS WITH POLYIMIDES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-05-07 US disclosed
US-5510425-A AROMATIC POLYIMIDE-EPOXY COPOLYMER MODIFIED BY BISMALEIMIDE COMPOUND; FLEXIBILITY, PEELING STRENGTH; COLDSETTING RESINS, ADHESIVES HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-04-23 US disclosed