Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557276 | 0.78 | ATM (0.38) | ATMMEN1KMT2AMAPK1POLB | |
| SCHEMBL18244792 | 0.74 | SLC22A1 (0.34) | ATMMEN1KMT2AMAPK1OPRM1 | |
| SCHEMBL6558542 | 0.71 | OPRM1 (0.45) | OPRM1ALDH1A1SMN1; SMN2OPRK1OPRD1 | |
| SCHEMBL25061772 | 0.70 | TP53 (0.39) | ATMMEN1KMT2AMAPK1POLB | |
| SCHEMBL18252889 | 0.67 | ATM (0.39) | ATMMEN1KMT2AMAPK1POLB | |
| SCHEMBL25061531 | 0.67 | ATM (0.36) | ATMMEN1KMT2AMAPK1POLB | |
| SCHEMBL25061577 | 0.65 | CRBN (0.33) | ATMMEN1KMT2AMAPK1POLB | |
| Hydrochloric Acid SCHEMBL25436233 | 0.64 | MEN1 (0.33) | ATMMEN1KMT2AMAPK1POLB | |
| SCHEMBL23618125 | 0.63 | KMT2A (0.36) | MEN1KMT2APOLBNFKB1CYP2C19 | |
| SCHEMBL18252879 | 0.61 | POLB (0.32) | ATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038877-B1 | Binaphthol monophosphoric acid derivative and its use | TOSOH CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6274745-B1 | CATALYST | TOSOH CORPORATION (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-1038877-A1 | Binaphthol monophosphoric acid derivative and its use | Tosoh Corporation (JP) | 2000-09-27 | — | — | EP | disclosed |