Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.45 |
| ▸ | METAP1 | P53582 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.38 |
| ▸ | IL1RN | P18510 | 4/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CLPP | Q16740 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558594 | 1.00 | METAP2 (0.45) | METAP2METAP1MMP9MMP8MMP14 | |
| SCHEMBL6559351 | 0.93 | METAP2 (0.45) | METAP2METAP1MMP9MMP8MMP14 | |
| SCHEMBL6559229 | 0.93 | METAP2 (0.45) | METAP2METAP1MMP9MMP8MMP14 | |
| Hydrochloric Acid SCHEMBL6559256 | 0.93 | METAP2 (0.45) | METAP2METAP1MMP9MMP8MMP14 | |
| SCHEMBL29711383 | 0.92 | METAP2 (0.44) | METAP2METAP1MMP9MMP8MMP14 | |
| SCHEMBL6560488 | 0.92 | METAP2 (0.44) | METAP2METAP1MMP9MMP8MMP14 | |
| SCHEMBL6559357 | 0.92 | METAP2 (0.44) | METAP2METAP1MMP9MMP8MMP14 | |
| Hydrochloric Acid SCHEMBL6558816 | 0.91 | METAP2 (0.43) | METAP2METAP1MMP9MMP8MMP14 | |
| SCHEMBL6560842 | 0.91 | METAP2 (0.43) | METAP2METAP1MMP9MMP8MMP14 | |
| SCHEMBL6558918 | 0.90 | METAP2 (0.47) | METAP2METAP1MMP9MMP8MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |