Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641866 | 0.84 | HSD17B10 (0.60) | HSD17B10PDE7AKMT2AALDH1A1PDE4B | |
| SCHEMBL27775732 | 0.83 | HSD17B10 (0.58) | HSD17B10PDE7AKMT2AALDH1A1PDE4B | |
| SCHEMBL6556853 | 0.80 | ALDH1A1 (0.47) | HSD17B10PDE7AKMT2AALDH1A1LMNA | |
| SCHEMBL11300569 | 0.79 | HSD17B10 (0.62) | HSD17B10PDE7AKMT2AALDH1A1PDE4B | |
| SCHEMBL2815627 | 0.78 | HSD17B10 (0.51) | HSD17B10PDE7AKMT2AALDH1A1PDE4B | |
| SCHEMBL2817984 | 0.78 | HSD17B10 (0.51) | HSD17B10PDE7AKMT2AALDH1A1VCAM1 | |
| SCHEMBL26633331 | 0.78 | HSD17B10 (0.51) | HSD17B10KMT2AALDH1A1NR1H4LMNA | |
| SCHEMBL2816593 | 0.78 | HSD17B10 (0.51) | HSD17B10PDE7AKMT2AALDH1A1VCAM1 | |
| SCHEMBL29749675 | 0.78 | HSD17B10 (0.51) | HSD17B10PDE7AKMT2AALDH1A1NR1H4 | |
| SCHEMBL31318376 | 0.77 | HSD17B10 (0.60) | HSD17B10PDE7AKMT2AALDH1A1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976725-B1 | Process for the continuous preparation of amino-halogenophenyl alkyl thioethers | BAYER CHEMICALS AG (DE) | 2004-03-03 | — | — | EP | claimed |