Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8676326 | 0.97 | — | — | |
| Iodide SCHEMBL8675588 | 0.97 | — | — | |
| SCHEMBL6557932 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL8676764 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL8676450 | 0.85 | MEN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8677448 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL8674746 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8675275 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL8673658 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL8678407 | 0.80 | BCHE (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705851-B9 | Catalyst systems and process for producing broad molecular weight distribution polyolefin | CONOCOPHILLIPS CO (US) | 2004-08-11 | — | — | EP | claimed |
| EP-0705851-B1 | Catalyst systems and process for producing broad molecular weight distribution polyolefin | CONOCOPHILLIPS CO (US) | 2004-01-21 | — | — | EP | claimed |
| EP-0726271-B1 | Organoaluminoxy product, catalyst systems, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2000-05-24 | — | — | EP | claimed |
| US-5670589-A | COORDINATION POLYMERIZATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-23 | — | — | US | claimed |
| US-5583189-A | USING A CATALYST SYSTEM COMPRISING THE REACTION PRODUCT OF A METALLOCENE COMPOUND, A SOLID ORGANOALUMINOXY PRODUCT AND AN ORGANOMETAL COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1996-12-10 | — | — | US | claimed |
| EP-0726271-A1 | Organoaluminoxy product, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-08-14 | — | — | EP | claimed |
| EP-0705851-A2 | Catalyst systems and process for producing broad molecular weight distribution polyolefin | PHILLIPS PETROLEUM COMPANY (US) | 1996-04-10 | — | — | EP | claimed |
| US-5496781-A | OLEFIN POLYMERIZATION | PHILLIPS PETROLEUM COMPANY (US) | 1996-03-05 | — | — | US | claimed |
| EP-0683179-A1 | Metallocene catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-11-22 | — | — | EP | claimed |
| EP-0726271-B1 | Organoaluminoxy product, catalyst systems, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5712404-A | REACTION OF FULVENE TYPE COMPOUND, AN ALKALI METAL COMPOUND AND TRANSITION METAL COMPOUND FOR CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-27 | — | — | US | disclosed |
| US-5670589-A | COORDINATION POLYMERIZATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-5583189-A | USING A CATALYST SYSTEM COMPRISING THE REACTION PRODUCT OF A METALLOCENE COMPOUND, A SOLID ORGANOALUMINOXY PRODUCT AND AN ORGANOMETAL COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0726271-A1 | Organoaluminoxy product, catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5496781-A | OLEFIN POLYMERIZATION | PHILLIPS PETROLEUM COMPANY (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0683179-A1 | Metallocene catalyst systems, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |