Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203707 | 0.81 | HSD17B10 (0.53) | MAPTSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL6199119 | 0.81 | NPSR1 (0.55) | MAPTMAPK1HSD17B10LMNAALDH1A1 | |
| SCHEMBL4513265 | 0.77 | HSD17B10 (0.56) | MAPTSMN1; SMN2TDP1CYP3A4HSD17B10 | |
| SCHEMBL13241715 | 0.75 | HSD17B10 (0.62) | SMN1; SMN2TDP1TSHRHSD17B10LMNA | |
| SCHEMBL4524457 | 0.74 | HSD17B10 (0.51) | SMN1; SMN2CYP3A4HSD17B10LMNAALDH1A1 | |
| SCHEMBL6556764 | 0.73 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL6558792 | 0.73 | MAPT (0.50) | MAPTSMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL30054040 | 0.73 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL30402470 | 0.73 | HSD17B10 (0.55) | MAPTSMN1; SMN2MCL1TDP1HSD17B10 | |
| SCHEMBL27875088 | 0.73 | MEN1 (0.57) | MAPTSMN1; SMN2TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | claimed |