Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16141098 | 0.75 | MAPT (0.66) | MAPTSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL531105 | 0.75 | MAPT (0.66) | MAPTSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL531104 | 0.75 | MAPT (0.66) | MAPTSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL30054040 | 0.74 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL6556764 | 0.74 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL218018 | 0.74 | MAPT (0.78) | MAPTSMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL1405705 | 0.73 | PTGS2 (0.56) | MAPTSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL1405711 | 0.73 | PTGS2 (0.56) | MAPTSMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL6558795 | 0.73 | MAPT (0.49) | MAPTSMN1; SMN2NPC1RAB9AMCL1 | |
| Dimethylformamide SCHEMBL27570110 | 0.73 | ERN1 (0.54) | MAPTTDP1CYP1A2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | claimed |