SCHEMBL6558976

SCHEMBL6558976

CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 1.00
L3MBTL1 Q9Y468 3/20 1.00
MAPK1 P28482 2/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
TSHR P16473 1/20 1.00
PHLPP2 Q6ZVD8 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
KDM4E B2RXH2 3/20 0.51
SLC2A1 P11166 1/20 0.50
POLB P06746 1/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
ALDH1A1 P00352 6/20 0.47
GAA P10253 1/20 0.47
CRHBP P24387 1/20 0.47
ATM Q13315 1/20 0.47
CRHR2 Q13324 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218018 0.88 MAPT (0.78) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
Phosphine SCHEMBL30201038 0.86 MAPT (0.75) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
Ammonia Solution, Strong SCHEMBL29558993 0.86 MAPT (0.75) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
Hydrogen Sulfide SCHEMBL28326954 0.86 MAPT (0.75) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
SCHEMBL9156652 0.86 MAPT (0.75) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
Iodide SCHEMBL10484653 0.84 MAPT (0.72) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
SCHEMBL1047553 0.84 MAPT (0.70) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
SCHEMBL6556688 0.84 MAPT (0.71) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
SCHEMBL5528929 0.82 MAPT (0.70) MAPTL3MBTL1MAPK1CYP1A2CYP3A4
SCHEMBL9948773 0.82 MAPT (0.70) MAPTL3MBTL1MAPK1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1100483-B1 GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS ABBOTT LAB (US) 2004-09-29 EP claimed
US-20230250364-A1 LAUNDRY CARE COMPOSITIONS, METHODS, AND TEST KITS FOR DETERMINING AUTHENTICITY PROCTER & GAMBLE (US) 2023-08-10 US disclosed
US-10889717-B2 Compositions, methods, and test kits for determining authenticity MILLIKEN & COMPANY (US) 2021-01-12 US disclosed
US-10274490-B2 Magnetic labeling of bacteria THE GENERAL HOSPITAL CORPORATION (US) 2019-04-30 US disclosed
US-20190112484-A1 COMPOSITIONS, METHODS, AND TEST KITS FOR DETERMINING AUTHENTICITY MILLIKEN & COMPANY 2019-04-18 US disclosed
US-20190112551-A1 LAUNDRY CARE COMPOSITIONS, METHODS, AND TEST KITS FOR DETERMINING AUTHENTICITY THE PROCTER & GAMBLE COMPANY 2019-04-18 US disclosed
US-20150125884-A1 Magnetic Labeling of Bacteria THE GENERAL HOSPITAL CORPORATION 2015-05-07 US disclosed
US-20150125884-A1 Magnetic Labeling of Bacteria THE GENERAL HOSPITAL CORPORATION 2015-05-07 US disclosed
WO-2013187954-A1 MAGNETIC LABELING OF BACTERIA THE GENERAL HOSPITAL CORPORATION (US) 2013-12-19 WO disclosed
EP-1767947-B1 An immunoassay method and kit to leucomalachite green and malachite green RANDOX LAB LTD (GB) 2008-10-29 EP disclosed
US-20070072242-A1 Immunoassay method and kit to leucomalachite green and malachite green RANDOX LABORATORIES LIMITED (GB) 2007-03-29 US disclosed
EP-1767947-A1 An immunoassay method and kit to leucomalachite green and malachite green Randox Laboratories Ltd. (GB) 2007-03-28 EP disclosed
US-6166013-A Glucocortiocoid-selective agents ABBOTT LABORATORIES (US) 2000-12-26 US disclosed
WO-1997017310-A1 REVERSIBLE CHARGE-BASED SEQUESTRATION ON SOLID SUPPORT VERSICOR, INC. (US) 1997-05-15 WO disclosed
US-5605616-A Reversible charge-based sequestration on solid support VERSICOR, INC. (US) 1997-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10889717-B2 Compositions, methods, and test kits for determining authenticity AHR, AR, ARSA MAPT 4529/4885L3MBTL1 1116/4885MAPK1 3710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.