Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558976 | 0.86 | MAPT (1.00) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL218018 | 0.85 | MAPT (0.78) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| Phosphine SCHEMBL30201038 | 0.83 | MAPT (0.75) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL29558993 | 0.83 | MAPT (0.75) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| Hydrogen Sulfide SCHEMBL28326954 | 0.83 | MAPT (0.75) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| Iodide SCHEMBL10484653 | 0.81 | MAPT (0.72) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL5528929 | 0.80 | MAPT (0.70) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL28140093 | 0.80 | MAPT (0.70) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL9948773 | 0.80 | MAPT (0.70) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11795354 | 0.78 | ALDH1A1 (0.58) | MAPTMAPK1L3MBTL1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407783-A | Thermostability, shelf life | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-04-18 | — | — | US | disclosed |