Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26073978 | 0.87 | TRPV4 (0.60) | TRPV4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7356053 | 0.87 | CA12 (0.61) | TRPV4TSHRCA12CA1CA2 | |
| SCHEMBL9093802 | 0.85 | TRPV4 (0.58) | TRPV4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30545664 | 0.85 | TRPV4 (0.58) | TRPV4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31649953 | 0.83 | TRPV4 (0.55) | TRPV4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2479567 | 0.80 | TRPV4 (0.53) | TRPV4CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14930253 | 0.80 | MEN1 (0.44) | TRPV4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29521706 | 0.78 | TSHR (0.70) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL184025 | 0.78 | TSHR (0.70) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8661729 | 0.78 | TRPV4 (0.50) | TRPV4TSHRKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202960-B1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI SYNTHELABO (FR) | 2004-03-10 | — | — | EP | claimed |
| US-6548702-B1 | Sulfonating m-hydroxybenzoic acid; methylation, salt formation, chlorination, reaction with t-butylamine | SANOFI-SYNTHELABO (FR) | 2003-04-15 | — | — | US | claimed |
| EP-1202960-A1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI-SYNTHELABO (FR) | 2002-05-08 | — | — | EP | claimed |
| WO-2001005754-A1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI-SYNTHELABO (FR) | 2001-01-25 | — | — | WO | claimed |
| CN-1164571-C | Method for preparing 2-methoxy-4- (N-tert-butylaminocarbonyl) benzenesulfonyl chloride | ��ŵ�Ѻϳ�ʵ���� | 2004-09-01 | — | — | CN | disclosed |
| CN-1164571-C | Method for preparing 2-methoxy-4- (N-tert-butylaminocarbonyl) benzenesulfonyl chloride | ��ŵ�Ѻϳ�ʵ���� | 2004-09-01 | — | — | CN | disclosed |
| EP-1202960-B1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI SYNTHELABO (FR) | 2004-03-10 | — | — | EP | disclosed |
| EP-1202960-B1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI SYNTHELABO (FR) | 2004-03-10 | — | — | EP | disclosed |
| US-6548702-B1 | Sulfonating m-hydroxybenzoic acid; methylation, salt formation, chlorination, reaction with t-butylamine | SANOFI-SYNTHELABO (FR) | 2003-04-15 | — | — | US | disclosed |
| US-6548702-B1 | Sulfonating m-hydroxybenzoic acid; methylation, salt formation, chlorination, reaction with t-butylamine | SANOFI-SYNTHELABO (FR) | 2003-04-15 | — | — | US | disclosed |
| US-20020128208-A1 | Nonpeptide agonists and antagonists of vasopressin receptors | EMORY UNIVERSITY | 2002-09-12 | — | — | US | disclosed |
| CN-1360569-A | Method for preparation of Z-methoxy-4-(N-t-butylamino-carbonyl)benzenesulfonyl chloride | SANOFI SYNTHELABO (FR) | 2002-07-24 | — | — | CN | disclosed |
| CN-1360569-A | Method for preparation of Z-methoxy-4-(N-t-butylamino-carbonyl)benzenesulfonyl chloride | SANOFI SYNTHELABO (FR) | 2002-07-24 | — | — | CN | disclosed |
| WO-2002047679-A2 | NONPEPTIDE AGONISTS AND ANTAGONISTS OF VASOPRESSIN RECEPTORS | EMORY UNIVERSITY (US) | 2002-06-20 | — | — | WO | disclosed |
| EP-1202960-A1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI-SYNTHELABO (FR) | 2002-05-08 | — | — | EP | disclosed |
| EP-1202960-A1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI-SYNTHELABO (FR) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001005754-A1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI-SYNTHELABO (FR) | 2001-01-25 | — | — | WO | disclosed |
| WO-2001005754-A1 | METHOD FOR THE PREPARATION OF 2-METHOXY-4-(N-T-BUTYLAMINO-CARBONYL)-BENZENESULFONYL CHLORIDE | SANOFI-SYNTHELABO (FR) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128208-A1 | Nonpeptide agonists and antagonists of vasopressin receptors | AVPR1A, AVPR2, AVPR1B | TRPV4 110/4885TSHR 95/4885CYP1A2 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.