Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.53 |
| ▸ | PPARA | Q07869 | 12/20 | 0.53 |
| ▸ | PPARD | Q03181 | 9/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559207 | 0.86 | PPARG (0.58) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6559789 | 0.85 | PPARD (0.71) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6559721 | 0.82 | PPARD (0.60) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7039142 | 0.81 | PPARA (0.75) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6938586 | 0.80 | PPARG (0.62) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7046234 | 0.80 | PPARD (0.62) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7044850 | 0.80 | PPARA (0.69) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL7046443 | 0.79 | PPARD (0.60) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6559245 | 0.79 | PPARA (0.75) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL6937885 | 0.78 | PPARG (0.73) | PPARGPPARAPPARDNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | claimed |