Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 10/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515503 | 0.77 | GAA (0.59) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17736002 | 0.76 | GAA (0.57) | GAAMAPTGRM4HTR2BMTNR1A | |
| SCHEMBL6562208 | 0.76 | GRM4 (0.55) | MAPTALDH1A1MEN1KMT2AGRM4 | |
| SCHEMBL16968461 | 0.75 | SMARCA2 (0.68) | ALDH1A1HPGDGRM2HSD17B10BCL2L1 | |
| Hydrochloric Acid SCHEMBL30557201 | 0.74 | SMARCA2 (0.67) | ALDH1A1HPGDGRM2HSD17B10BCL2L1 | |
| SCHEMBL2419571 | 0.74 | GAA (1.00) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22466170 | 0.72 | GAA (0.53) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22466022 | 0.72 | GAA (0.53) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL513941 | 0.72 | GAA (0.52) | GAAMAPTGRM4HTR2BMTNR1A | |
| SCHEMBL30260561 | 0.71 | SMARCA2 (0.43) | ALDH1A1HPGDHSD17B10BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |
| EP-1071670-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054314-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |