Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 10/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MELK | Q14680 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17736002 | 0.98 | GAA (0.57) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL513941 | 0.94 | GAA (0.52) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL12235677 | 0.87 | GRM4 (0.56) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL2189185 | 0.87 | GAA (0.50) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL1129152 | 0.87 | ALDH1A1 (0.48) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL18999306 | 0.84 | GRM4 (0.50) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL18999326 | 0.84 | GRM4 (0.50) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL23144535 | 0.82 | MAOA (0.53) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL20560807 | 0.82 | MEN1 (0.46) | GAAGRM4HTR2BMTNR1AKCNH2 | |
| SCHEMBL5990519 | 0.82 | MAPKAPK2 (0.64) | GAAGRM4KCNH2L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429219-A | Phenyl-pyrazole complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2009-05-13 | — | — | CN | claimed |
| CN-100387607-C | Phenyl-pyrazole complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2008-05-14 | — | — | CN | claimed |
| CN-116655536-A | Class N 1 -aryl-3-fluoroalkyl-5-fluoropyrazole compound, and preparation method and application thereof | 天津大学 | 2023-08-29 | — | — | CN | disclosed |
| US-20230000982-A1 | COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING NOVEL TRIFLUOROMETHYL PHENYL PYRAZOLE DERIVATIVE AS ACTIVE INGREDIENT | KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) | 2023-01-05 | — | — | US | disclosed |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | UNIV SOUTHERN CALIFORNIA (US) | 2020-12-10 | — | — | US | disclosed |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2020-08-11 | — | — | US | disclosed |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2020-08-11 | — | — | US | disclosed |
| EP-3109238-B1 | PHENYL-PYRAZOLE COMPLEXES OF IRIDIUM | UNIV SOUTHERN CALIFORNIA (US) | 2019-09-18 | — | — | EP | disclosed |
| US-9972802-B2 | Organic electroluminescent element | Konica Minolta, Inc. (JP) | 2018-05-15 | — | — | US | disclosed |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2018-01-18 | — | — | US | disclosed |
| US-20080176102-A1 | Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes | THOMPSON MARK E | 2008-07-24 | — | — | US | disclosed |
| CN-100387607-C | Phenyl-pyrazole complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2008-05-14 | — | — | CN | disclosed |
| US-7338722-B2 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-03-04 | — | — | US | disclosed |
| CN-1788012-A | Phenyl-pyrazole complexes of Ir | UNIV SOUTHERN CALIFORNIA (US) | 2006-06-14 | — | — | CN | disclosed |
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | UNIVERSITY OF SOUTHERN CALIFORNIA, THE | 2004-12-16 | — | — | US | disclosed |
| US-4058391-A | 1,2-Dialkyl-3,4,5-trisubstituted pyrazolium salts as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1977-11-15 | — | — | US | disclosed |
| US-4041046-A | INTERMEDIATES FOR THE CORRESPONDING HERBICIDAL PYRAZOLIUM SALTS ON | AMERICAN CYANAMID COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
| US-4009277-A | 1,2-Dialkyl-3,4,5-trisubstituted pyrazolium salts as fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3963742-A | 1,2-Dialkyl-3,4,5-trisubstituted pyrazolium salts as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040253478-A1 | Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; | NR2E3, IK, NR2C2 | GAA 4786/4885GRM4 602/4885HTR2B 3042/4885 |
| US-20200388773-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir | EML4, RCOR3, CPNE4 | GAA 4601/4885GRM4 259/4885HTR2B 1325/4885 |
| US-20180019413-A1 | Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexes of Ir | EML4, AFF4, RCOR3 | GAA 4560/4885GRM4 237/4885HTR2B 1155/4885 |
| US-20080176102-A1 | Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes | EML4, RNF4, LIG4 | GAA 4678/4885GRM4 127/4885HTR2B 2741/4885 |
| US-20230000982-A1 | COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING NOVEL TRIFLUOROMETHYL PHENYL PYRAZOLE DERIVATIVE AS ACTIVE INGREDIENT | CASP3, API5, HDAC1 | GAA 3740/4885GRM4 4609/4885HTR2B 4357/4885 |
| US-10741775-B2 | Phenyl and fluorenyl substituted phenyl-pyrazole complexes of Ir | EML4, AFF4, RCOR3 | GAA 4560/4885GRM4 237/4885HTR2B 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.