Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333513 | 0.87 | HTT (0.50) | KMT2ATRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12674419 | 0.86 | S1PR2 (0.47) | KMT2ATRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8989811 | 0.86 | KMT2A (0.43) | KMT2ATRPV3HTR2CTLR8TAAR1 | |
| SCHEMBL28903882 | 0.82 | TRPV3 (0.35) | KMT2ATRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11818115 | 0.81 | KDM4E (0.53) | KMT2ATRPV3LMNAKDM4E | |
| Bromide SCHEMBL11824197 | 0.80 | BRD4 (0.45) | TRPV3LMNAHIF1AKDM4E | |
| SCHEMBL17069296 | 0.77 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3HTR2CCYP2D6 | |
| SCHEMBL3103040 | 0.77 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3HTR2CCYP2D6 | |
| SCHEMBL17069299 | 0.77 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3HTR2CCYP2D6 | |
| SCHEMBL7469957 | 0.77 | S1PR3 (0.47) | KMT2ATRPV3TLR8LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038877-B1 | Binaphthol monophosphoric acid derivative and its use | TOSOH CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6274745-B1 | CATALYST | TOSOH CORPORATION (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-1038877-A1 | Binaphthol monophosphoric acid derivative and its use | Tosoh Corporation (JP) | 2000-09-27 | — | — | EP | disclosed |