Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.52 |
| ▸ | METAP1 | P53582 | 3/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559031 | 1.00 | METAP2 (0.52) | METAP2METAP1ITGB3ITGA2BMMP12 | |
| SCHEMBL29885383 | 1.00 | METAP2 (0.52) | METAP2METAP1ITGB3ITGA2BMMP12 | |
| Hydrochloric Acid SCHEMBL6558941 | 0.99 | METAP2 (0.51) | METAP2METAP1ITGB3ITGA2BMMP12 | |
| Hydrochloric Acid SCHEMBL6558928 | 0.99 | METAP2 (0.51) | METAP2METAP1ITGB3ITGA2BMMP12 | |
| SCHEMBL7784058 | 0.86 | METAP2 (0.47) | METAP2METAP1GPR88SOAT1 | |
| Hydrochloric Acid SCHEMBL7784059 | 0.85 | METAP2 (0.46) | METAP2METAP1GPR88SOAT1 | |
| Hydrochloric Acid SCHEMBL7784056 | 0.85 | METAP2 (0.46) | METAP2METAP1GPR88SOAT1 | |
| SCHEMBL6559295 | 0.84 | METAP2 (0.47) | METAP2METAP1ITGB3ITGA2BMMP12 | |
| SCHEMBL6559201 | 0.84 | METAP2 (0.47) | METAP2METAP1MMP3GPR88SMN1; SMN2 | |
| SCHEMBL6559219 | 0.84 | METAP2 (0.47) | METAP2METAP1MMP3GPR88SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |