Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558980 | 0.91 | LMNA (0.40) | LMNATDP1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6558950 | 0.87 | LMNA (0.44) | LMNAKDM4EADRA2AADRA2CHIF1A | |
| SCHEMBL6559691 | 0.84 | LMNA (0.44) | LMNAAOC3KDM4EADRA2AADRA2C | |
| SCHEMBL10534307 | 0.84 | NPC1 (0.40) | LMNATDP1ALDH1A1 | |
| SCHEMBL6558908 | 0.82 | LMNA (0.46) | LMNAKDM4EADRA2AADRA2CHIF1A | |
| SCHEMBL6560720 | 0.82 | LMNA (0.44) | LMNAHSD17B10AOC3KDM4EADRA2A | |
| SCHEMBL6558628 | 0.81 | LMNA (0.44) | LMNAAOC3KDM4EADRA2AADRA2C | |
| SCHEMBL4594703 | 0.80 | LMNA (0.50) | LMNATDP1HSD17B10AOC3KDM4E | |
| SCHEMBL18312620 | 0.79 | HTT (0.43) | LMNAAOC3KDM4EADRA2ACHRM2 | |
| SCHEMBL29277742 | 0.79 | HTT (0.43) | LMNAAOC3KDM4EADRA2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735403-B1 | Liquid crystal orienting agent | JSR CORP (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-5700860-A | Liquid crystal orienting agent | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0735403-A1 | Liquid crystal orienting agent | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |