Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.35 |
| ▸ | CTSD | P07339 | 4/20 | 0.32 |
| ▸ | BACE1 | P56817 | 4/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559536 | 1.00 | SIRT2 (0.37) | SIRT2SIRT1TRPV1CTSDBACE1 | |
| SCHEMBL6559929 | 0.96 | SIRT2 (0.38) | SIRT2SIRT1TRPV1CTSDBACE1 | |
| SCHEMBL6560804 | 0.84 | TRPV1 (0.48) | TRPV1CTSDBACE1 | |
| SCHEMBL6560865 | 0.83 | KCNE1 (0.43) | SIRT2SIRT1TRPV1 | |
| SCHEMBL6559299 | 0.83 | KCNE1 (0.43) | SIRT2SIRT1TRPV1 | |
| SCHEMBL6558219 | 0.82 | TRPV1 (0.39) | SIRT2SIRT1TRPV1CTSDBACE1 | |
| SCHEMBL6559514 | 0.82 | TRPV1 (0.39) | SIRT2SIRT1TRPV1CTSDBACE1 | |
| SCHEMBL6558741 | 0.81 | TRPV1 (0.33) | SIRT2TRPV1CTSDBACE1BACE2 | |
| SCHEMBL6559265 | 0.80 | TRPV1 (0.38) | SIRT2SIRT1TRPV1CTSDBACE1 | |
| SCHEMBL6559316 | 0.80 | TRPV1 (0.38) | SIRT2SIRT1TRPV1CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |