Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 6/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 7/20 | 0.32 |
| ▸ | PPARA | Q07869 | 7/20 | 0.32 |
| ▸ | PPARG | P37231 | 7/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559384 | 0.85 | PPARG (0.36) | LTB4RLTB4R2PPARDPPARAPPARG | |
| SCHEMBL7044166 | 0.81 | CETP (0.40) | LTB4RPPARDPPARAPPARG | |
| SCHEMBL7044586 | 0.77 | PPARG (0.32) | LTB4RLTB4R2PPARDPPARAPPARG | |
| SCHEMBL7044794 | 0.73 | PPARA (0.40) | PPARDPPARAPPARG | |
| SCHEMBL8444660 | 0.72 | LTB4R (0.37) | LTB4RLTB4R2PPARDPPARAPPARG | |
| SCHEMBL6940262 | 0.66 | PPARG (0.46) | PPARDPPARAPPARG | |
| SCHEMBL6938366 | 0.62 | PPARG (0.50) | PPARDPPARAPPARG | |
| SCHEMBL6559176 | 0.61 | PPARG (0.49) | LTB4RLTB4R2PPARDPPARAPPARG | |
| SCHEMBL11031713 | 0.55 | SUCNR1 (0.40) | — | |
| SCHEMBL2406964 | 0.55 | PPARG (0.56) | LTB4RLTB4R2PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | claimed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | claimed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | claimed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | disclosed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | disclosed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |