Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489596 | 0.85 | TSHR (0.71) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 | |
| SCHEMBL20145597 | 0.84 | TSHR (0.75) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 | |
| SCHEMBL19348478 | 0.79 | KMT2A (0.67) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 | |
| SCHEMBL10884111 | 0.76 | KMT2A (0.51) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 | |
| SCHEMBL13692619 | 0.75 | KMT2A (0.54) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 | |
| SCHEMBL5455308 | 0.74 | KMT2A (0.53) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 | |
| SCHEMBL4001721 | 0.74 | KMT2A (0.52) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 | |
| SCHEMBL6559920 | 0.74 | PKM (0.44) | TSHRCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3245089 | 0.73 | CYP3A4 (0.60) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 | |
| SCHEMBL7650437 | 0.72 | KMT2A (0.58) | KMT2AL3MBTL1TSHRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436255-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003024924-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-03-27 | — | — | WO | claimed |