Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.50 |
| ▸ | PPARD | Q03181 | 17/20 | 0.50 |
| ▸ | PPARA | Q07869 | 17/20 | 0.50 |
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559385 | 0.93 | PPARA (0.53) | PPARGPPARDPPARAPTGIRTBXA2R | |
| SCHEMBL7044719 | 0.86 | PPARA (0.55) | PPARGPPARDPPARA | |
| SCHEMBL6559847 | 0.81 | PPARG (0.56) | PPARGPPARDPPARA | |
| SCHEMBL7046187 | 0.80 | PPARA (0.57) | PPARGPPARDPPARA | |
| SCHEMBL6559379 | 0.78 | PPARG (0.61) | PPARGPPARDPPARA | |
| SCHEMBL6560063 | 0.76 | PPARA (0.56) | PPARGPPARDPPARA | |
| SCHEMBL6560061 | 0.73 | PPARG (0.63) | PPARGPPARDPPARA | |
| SCHEMBL7993954 | 0.71 | PPARA (0.53) | PPARGPPARDPPARA | |
| SCHEMBL6559869 | 0.70 | PPARA (0.48) | PPARGPPARDPPARAPTGESALOX5 | |
| SCHEMBL6559284 | 0.69 | PPARG (0.72) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | claimed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | claimed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | claimed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | disclosed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | disclosed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |