Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.60 |
| ▸ | DRD4 | P21917 | 6/20 | 0.60 |
| ▸ | DRD3 | P35462 | 5/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | DRD1 | P21728 | 3/20 | 0.53 |
| ▸ | HRH2 | P25021 | 3/20 | 0.53 |
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558994 | 0.91 | DRD2 (0.59) | DRD2DRD4DRD3CHRM1HRH4 | |
| Hydrochloric Acid SCHEMBL7411216 | 0.86 | CHRM1 (0.73) | DRD2DRD4DRD3CHRM1HRH4 | |
| SCHEMBL10194132 | 0.74 | MEN1 (0.63) | DRD2DRD4DRD3CHRM1HRH4 | |
| SCHEMBL7411296 | 0.74 | DRD3 (0.76) | DRD2DRD4DRD3CHRM1HRH4 | |
| SCHEMBL31098210 | 0.74 | HRH4 (0.73) | DRD2DRD4DRD3CHRM1HRH4 | |
| SCHEMBL10194061 | 0.74 | HTR2C (0.67) | DRD2DRD4DRD3CHRM1HRH4 | |
| SCHEMBL7412526 | 0.73 | DRD4 (0.49) | DRD2DRD4DRD3CHRM1HRH4 | |
| SCHEMBL10194134 | 0.73 | MEN1 (0.61) | DRD2DRD4DRD3CHRM1HRH4 | |
| SCHEMBL19096125 | 0.73 | HRH4 (0.68) | DRD2DRD4DRD3CHRM1HRH4 | |
| SCHEMBL7407008 | 0.73 | DRD3 (0.55) | DRD2DRD4DRD3CHRM1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252151-B1 | A PROCESS FOR THE PREPARATION OF QUETIAPINE AND INTERMEDIATES THEREFOR | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2004-03-17 | — | — | EP | disclosed |