SCHEMBL6560355

SCHEMBL6560355

CC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CO[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6343019 1.00 CYP1A2 (0.33) CYP1A2CYP2C9CYP2C19RECQLUSP2
SCHEMBL18419600 0.98 CYP1A2 (0.31) CYP1A2CYP2C9CYP2C19RECQL
SCHEMBL8815284 0.76
SCHEMBL622534 0.76
SCHEMBL6269402 0.74 CYP1A2 (0.31) CYP1A2CYP2C9CYP2C19RECQL
SCHEMBL15644868 0.73 LMNA (0.33)
SCHEMBL28585604 0.73 LMNA (0.33)
SCHEMBL8374217 0.73
SCHEMBL15215217 0.73 USP2 (0.34) CYP1A2CYP2C9CYP2C19RECQLUSP2
SCHEMBL15215216 0.73 USP2 (0.34) CYP1A2CYP2C9CYP2C19RECQLUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790522-B1 Process for forming a liquid crystal vertical alignment film NISSAN CHEMICAL IND LTD (JP) 2004-03-24 EP claimed
US-5766673-A POLYSILOXANES MODIFIED WITH AN ALCOHOL AND OXALIC ACID NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-16 US claimed
EP-0790522-A1 Process for forming a liquid crystal vertical alignment film NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1997-08-20 EP claimed
US-12091512-B2 Organopolysiloxane and coating composition containing organopolysiloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-09-17 US disclosed
US-20220340715-A1 ORGANOPOLYSILOXANE AND COATING COMPOSITION CONTAINING ORGANOPOLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-10-27 US disclosed