Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 6/20 | 0.37 |
| ▸ | NOS1 | P29475 | 6/20 | 0.37 |
| ▸ | NOS2 | P35228 | 6/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 3/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069209 | 0.89 | NOS3 (0.38) | NOS3NOS1NOS2RIPK1GHSR | |
| SCHEMBL6069550 | 0.80 | NOS3 (0.39) | NOS3NOS1NOS2RIPK1GHSR | |
| SCHEMBL6069478 | 0.73 | NOS3 (0.59) | NOS3NOS1NOS2GHSR | |
| SCHEMBL6069537 | 0.72 | NOS3 (0.49) | NOS3NOS1NOS2RIPK1GHSR | |
| Hydrochloric Acid SCHEMBL6069850 | 0.72 | NOS3 (0.52) | NOS3NOS1NOS2 | |
| SCHEMBL6069538 | 0.72 | NOS3 (0.57) | NOS3NOS1NOS2GHSR | |
| SCHEMBL6069204 | 0.70 | NOS3 (0.56) | NOS3NOS1NOS2GHSR | |
| SCHEMBL6069521 | 0.70 | NOS3 (0.50) | NOS3NOS1NOS2RIPK1GHSR | |
| SCHEMBL6069203 | 0.70 | NOS3 (0.51) | NOS3NOS1NOS2RIPK1GHSR | |
| SCHEMBL6069425 | 0.69 | NOS3 (0.46) | NOS3NOS1NOS2SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115708-B1 | AMINOALKYL-3,4-DIHYDROQUINOLINE DERIVATES AS NO-SYNTHASE INHIBITORS | SCHERING AG (DE) | 2004-04-14 | — | — | EP | claimed |