Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5949168 | 1.00 | CYP2D6 (0.56) | CYP2D6FDPSMEN1LMNATP53 | |
| SCHEMBL6560568 | 1.00 | CYP2D6 (0.56) | CYP2D6FDPSMEN1LMNATP53 | |
| SCHEMBL10679403 | 0.84 | CYP2D6 (0.62) | CYP2D6CYP1A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5949272 | 0.81 | CYP2D6 (0.53) | CYP2D6FDPSMEN1LMNATP53 | |
| SCHEMBL465920 | 0.80 | CYP2D6 (0.58) | CYP2D6CYP1A2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20833013 | 0.80 | CYP2D6 (0.56) | CYP2D6LMNACYP1A2TSHRSLC6A2 | |
| SCHEMBL22259900 | 0.80 | CYP2D6 (0.56) | CYP2D6LMNACYP1A2TSHRSLC6A2 | |
| SCHEMBL20832991 | 0.80 | CYP2D6 (0.56) | CYP2D6LMNACYP1A2TSHRSLC6A2 | |
| SCHEMBL8507267 | 0.80 | CYP2D6 (0.56) | CYP2D6LMNACYP1A2TSHRSLC6A2 | |
| SCHEMBL11536391 | 0.79 | HSD17B10 (0.61) | CYP2D6FDPSMEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050531-B1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | SERVIER LAB (FR) | 2004-11-17 | — | — | EP | disclosed |
| EP-1050531-A1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |