Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 6/20 | 0.36 |
| ▸ | MMP3 | P08254 | 4/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559341 | 0.89 | METAP2 (0.44) | METAP2METAP1SCN9AMMP2MMP3 | |
| SCHEMBL6559295 | 0.87 | METAP2 (0.47) | METAP2METAP1CYP26A1MMP3GPR88 | |
| SCHEMBL6559219 | 0.86 | METAP2 (0.47) | METAP2METAP1MMP2MMP3RIPK1 | |
| SCHEMBL6559201 | 0.86 | METAP2 (0.47) | METAP2METAP1MMP2MMP3RIPK1 | |
| Hydrochloric Acid SCHEMBL6560458 | 0.85 | METAP2 (0.46) | METAP2METAP1MMP2MMP3RIPK1 | |
| Hydrochloric Acid SCHEMBL6560449 | 0.85 | METAP2 (0.46) | METAP2METAP1MMP2MMP3RIPK1 | |
| SCHEMBL6558831 | 0.85 | METAP2 (0.49) | METAP2METAP1CYP26A1MMP2MMP3 | |
| SCHEMBL6560877 | 0.85 | METAP2 (0.47) | METAP2METAP1MMP2MMP3GPR88 | |
| SCHEMBL6560569 | 0.85 | METAP2 (0.40) | METAP2METAP1SMN1; SMN2 | |
| SCHEMBL6559017 | 0.84 | METAP2 (0.47) | METAP2METAP1MMP2MMP3GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |