Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14751337 | 0.74 | CA1 (0.44) | KMT2ABTK | |
| SCHEMBL31368028 | 0.72 | MAPK1 (0.37) | HRH3BTK | |
| Hydrochloric Acid SCHEMBL31368151 | 0.71 | MAPK1 (0.36) | HRH3BTK | |
| SCHEMBL5722453 | 0.70 | KMT2A (0.32) | HRH3KMT2ABTK | |
| SCHEMBL17883906 | 0.69 | HRH3 (0.39) | HRH3KMT2ABTKMMP2ANPEP | |
| SCHEMBL17883938 | 0.69 | HRH3 (0.39) | HRH3KMT2ABTKMMP2ANPEP | |
| SCHEMBL3405894 | 0.69 | HRH3 (0.39) | HRH3KMT2ABTKMMP2ANPEP | |
| SCHEMBL7234338 | 0.69 | GAA (0.34) | — | |
| SCHEMBL1298062 | 0.69 | HRH3 (0.43) | HRH3KMT2ABTK | |
| SCHEMBL7897286 | 0.69 | CA1 (0.32) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933993-A4 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0933993-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS INC. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997047194-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |