Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722384 | 0.82 | SLC6A12 (0.34) | BTKHRH3 | |
| SCHEMBL5722385 | 0.80 | SLC6A12 (0.39) | — | |
| SCHEMBL17249604 | 0.79 | — | — | |
| SCHEMBL31368028 | 0.73 | MAPK1 (0.37) | BTKHRH3 | |
| Hydrochloric Acid SCHEMBL31368151 | 0.72 | MAPK1 (0.36) | BTKHRH3 | |
| SCHEMBL17883938 | 0.70 | HRH3 (0.39) | KMT2ABTKHRH3 | |
| SCHEMBL3405894 | 0.70 | HRH3 (0.39) | KMT2ABTKHRH3 | |
| SCHEMBL17883906 | 0.70 | HRH3 (0.39) | KMT2ABTKHRH3 | |
| SCHEMBL6560716 | 0.70 | HRH3 (0.35) | KMT2ABTKHRH3 | |
| SCHEMBL1298062 | 0.70 | HRH3 (0.43) | KMT2ABTKHRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933993-B1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2006-04-05 | — | — | EP | disclosed |
| US-6410594-B1 | VIRICIDES | BIOCRYST PHARMACEUTICALS, INC. | 2002-06-25 | — | — | US | disclosed |