SCHEMBL6560722

SCHEMBL6560722

Nc1ccccc1C(=O)Nc1ccc2c(O)cc(S(=O)(=O)O)cc2c1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 3/20 0.67
CTDSP1 Q9GZU7 1/20 0.67
PRMT1 Q99873 2/20 0.64
NSD2 O96028 2/20 0.54
DUSP3 P51452 2/20 0.54
PTPN5 P54829 2/20 0.54
PTPN11 Q06124 2/20 0.54
NT5E P21589 2/20 0.54
SIRT1 Q96EB6 1/20 0.49
FADS1 O60427 3/20 0.48
CASP7 P55210 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PTGS1 P23219 2/20 0.45
ENPP2 Q13822 1/20 0.45
P2RX1 P51575 1/20 0.44
APEX1 P27695 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561236 0.92 NT5E (0.66) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL8099566 0.87 PRMT1 (0.66) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL11426166 0.85 CASP6 (0.64) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL11440916 0.85 CASP6 (0.64) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL3830931 0.83 CASP6 (0.77) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL2184239 0.81 CASP6 (1.00) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL29495050 0.81 CASP6 (1.00) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL6560617 0.80 CASP6 (0.77) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL30646175 0.80 CASP6 (0.98) CASP6CTDSP1PRMT1NSD2DUSP3
SCHEMBL14413308 0.80 CASP6 (0.98) CASP6CTDSP1PRMT1NSD2DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055710-B1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-08-11 EP disclosed
US-6444794-B1 COMPLEXING WITH SUBSTRATE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-09-03 US disclosed
EP-0675172-B1 Water-solable azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-11 EP disclosed
EP-1055710-A1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-29 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
CN-1235992-A Water-soluble fiber-reactive dyes, processes for their preparation and their use HOECHST AG (DE) 1999-11-24 CN disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0575744-A1 Silane-containing dyestuffs, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-29 EP disclosed
US-5225544-A FIBER REACTIVE DYES WHICH CONTAIN A CYANOAMINOTRIAZINYL GROUP AND ONE OR TWO GROUPS OF THE VINYL SULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0548795-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0542079-A2 Process for continuously reacting halogenopyrimidines with amines BAYER AG (DE) 1993-05-19 EP disclosed
EP-0542214-A2 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
US-5091515-A PROCESS FOR THE PREPARATION OF SUBSTITUTED 2,4-DIAMINO-6-FLUORO-S-TRIAZINES BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
EP-0272532-B1 DYESTUFFS BAYER AG (DE) 1991-05-29 EP disclosed
EP-0272532-A2 Dyestuffs BAYER AG (DE) 1988-06-29 EP disclosed