Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 11/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559736 | 0.89 | PHGDH (0.62) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6559686 | 0.88 | PHGDH (0.57) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6562659 | 0.86 | PHGDH (0.54) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6562212 | 0.86 | PHGDH (0.44) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6657881 | 0.84 | PHGDH (0.56) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6561388 | 0.82 | PHGDH (0.52) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6653887 | 0.80 | PHGDH (0.52) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6966126 | 0.79 | PHGDH (0.51) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6651041 | 0.79 | MAPT (0.52) | PHGDHCYP3A4MEN1KMT2APKM | |
| SCHEMBL6955729 | 0.79 | PHGDH (0.51) | PHGDHCYP3A4MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075469-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2004-05-26 | — | — | EP | disclosed |
| US-6683184-B2 | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| US-20030092910-A1 | Piperazine derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092910-A1 | Piperazine derivatives and process for the preparation thereof | CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS | PHGDH 2923/4885CYP3A4 339/4885MEN1 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.