Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.51 |
| ▸ | HNF4A | P41235 | 3/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.46 |
| ▸ | RARG | P13631 | 4/20 | 0.46 |
| ▸ | RARA | P10276 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 4/20 | 0.45 |
| ▸ | RXRG | P48443 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032583 | 0.90 | RARB (0.54) | RXRAHNF4ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL6561502 | 0.89 | RXRA (0.51) | RXRAHNF4ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL6033229 | 0.88 | RXRA (0.53) | RXRAHNF4ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL6032628 | 0.87 | RXRA (0.43) | RXRAHNF4ACYP3A4RARBRARG | |
| SCHEMBL6562225 | 0.87 | RXRA (0.49) | RXRAHNF4ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL6033092 | 0.86 | RXRA (0.51) | RXRAHNF4ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL6562290 | 0.83 | RXRA (0.48) | RXRAHNF4ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL6559631 | 0.83 | RXRA (0.51) | RXRAHNF4ARARBRARGRARA | |
| SCHEMBL6032623 | 0.83 | RARG (0.61) | RXRAHNF4ACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL6032616 | 0.80 | RXRA (0.47) | RXRAHNF4ACYP26A1CYP3A4CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086080-B1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2004-08-25 | — | — | EP | disclosed |
| EP-1086080-A1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065872-A1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 1999-12-23 | — | — | WO | disclosed |