SCHEMBL6560852

SCHEMBL6560852

CO[Si](CCC(F)(F)F)(OC)N1CCC(C)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9171843 0.82
SCHEMBL8075305 0.76 HPGD (0.33)
SCHEMBL5584286 0.73
SCHEMBL5584285 0.73
SCHEMBL7621896 0.70 POLB (0.38)
SCHEMBL5584096 0.69 PEPD (0.31)
SCHEMBL5584404 0.68 PEPD (0.30)
SCHEMBL5584140 0.68
SCHEMBL137670 0.68 KMT2A (0.32)
Nanofin SCHEMBL6561177 0.67 CYP2C9 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0926164-B1 Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them BASELL NORTH AMERICA INC (US) 2004-02-25 EP disclosed
US-6130180-A Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds MONTELL NORTH AMERICA INC. (US) 2000-10-10 US disclosed
EP-0926164-A2 Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them MONTELL NORTH AMERICA INC. (US) 1999-06-30 EP disclosed
EP-0473899-B1 Catalyst for the Polymerization of alpha-olefins containing trifluoropropyl substituted silane compounds HIMONT INC (US) 1995-04-26 EP disclosed
US-5102842-A Coordination catalyst HIMONT INCORPORATED (US) 1992-04-07 US disclosed
EP-0473899-A2 Catalyst for the Polymerization of alpha-olefins containing trifluoropropyl substituted silane compounds Himont Incorporated (US) 1992-03-11 EP disclosed