SCHEMBL8075305

SCHEMBL8075305

CCCC[Si](OC)(OC)N1CCC(C)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6560852 0.76 PHGDH (0.31)
SCHEMBL14460047 0.76 GNAI3 (0.31)
SCHEMBL9279208 0.74 LMNA (0.34) TSHRL3MBTL1
SCHEMBL9282463 0.73 L3MBTL1 (0.34) L3MBTL1HRH3
SCHEMBL7621896 0.73 POLB (0.38) ALDH1A1TSHRL3MBTL1
SCHEMBL8073767 0.68 CARM1 (0.35) HPGDALDH1A1TSHRL3MBTL1NPC1
SCHEMBL13835821 0.67 SMN1; SMN2 (0.33) HPGDALDH1A1TSHRNPC1
SCHEMBL3016334 0.66 CARM1 (0.54) HRH3
SCHEMBL9517605 0.66 CARM1 (0.44) ALDH1A1HRH3
SCHEMBL14460043 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6165930-A Organosilane compounds MONTELL NORTH AMERICA INC. (US) 2000-12-26 US disclosed
EP-0410443-B1 Organosilane compounds HIMONT INC (US) 1995-01-11 EP disclosed
US-5166340-A Polymerization catalysts, coordination catalysts for olefin polymerization HIMONT INCORPORATED (US) 1992-11-24 US disclosed
EP-0410443-A1 Organosilane compounds MONTELL NORTH AMERICA INC. (US) 1991-01-30 EP disclosed