Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056947 | 0.90 | HTT (0.38) | HTTTLR8TDP1MAPK1ESR1 | |
| SCHEMBL8056949 | 0.90 | HTT (0.38) | HTTTLR8TDP1MAPK1ESR1 | |
| SCHEMBL2560478 | 0.83 | ESR1 (0.43) | HTTTLR8TDP1MAPK1ESR1 | |
| SCHEMBL2558944 | 0.81 | HTT (0.43) | HTTTLR8TDP1MAPK1ESR1 | |
| SCHEMBL384778 | 0.79 | HTT (0.55) | HTTTLR8TDP1MAPK1IDO1 | |
| SCHEMBL7077343 | 0.79 | ESR1 (0.34) | HTTESR1 | |
| SCHEMBL2556340 | 0.74 | HTR1A (0.46) | TDP1MAPK1ESR1KDM4EALDH1A1 | |
| SCHEMBL2556651 | 0.74 | ESR1 (0.51) | HTTTLR8TDP1MAPK1ESR1 | |
| SCHEMBL2563362 | 0.73 | HTT (0.37) | HTTTLR8ESR1IDO1MCHR1 | |
| SCHEMBL13475561 | 0.72 | ESR1 (0.49) | HTTTLR8TDP1MAPK1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1078970-B1 | DPP-containing conjugated polymers and electroluminescent devices | CIBA SC HOLDING AG (CH) | 2004-03-17 | — | — | EP | disclosed |
| US-6451459-B1 | DIKETOPYRROLOPYRROLE (DPP) BASED POLYMERS AND COPOLYMERS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-17 | — | — | US | disclosed |
| EP-1078970-A1 | DPP-containing conjugated polymers and electroluminescent devices | Ciba SC Holding AG (CH) | 2001-02-28 | — | — | EP | disclosed |
| US-6114490-A | ELECTROLUMINESCENCE MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |